BDBM50079943 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-phenyl-piperidin-4-ylmethyl)-amine::CHEMBL112033

SMILES: C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1

InChI Key: InChIKey=DXFCGSGBNDZTRJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50079943 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O2/c1-2-6-18(7-3-1)23-12-10-17(11-13-23)14-22-15-19-16-24-20-8-4-5-9-21(20)25-19/h1-9,17,19,22H,10-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligand				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50079943 ((2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pheny...) Show SMILES C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C21H26N2O2/c1-2-6-18(7-3-1)23-12-10-17(11-13-23)14-22-15-19-16-24-20-8-4-5-9-21(20)25-19/h1-9,17,19,22H,10-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Knoll Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound to the dopamine receptor D2L in rat brain membranes				J Med Chem 42: 3342-55 (1999) Article DOI: 10.1021/jm9910122 BindingDB Entry DOI: 10.7270/Q2WH2P6K
					More data for this Ligand-Target Pair