BDBM50080073 CHEMBL3415960

SMILES: Nc1nc2ncc(CNc3ccc(cc3)C(=O)NCCCC(=O)NO)nc2c(=O)[nH]1

InChI Key: InChIKey=CQHIVIIIAAJVRB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50080073 (CHEMBL3415960) Show SMILES Nc1nc2ncc(CNc3ccc(cc3)C(=O)NCCCC(=O)NO)nc2c(=O)[nH]1 Show InChI InChI=1S/C18H20N8O4/c19-18-24-15-14(17(29)25-18)23-12(9-22-15)8-21-11-5-3-10(4-6-11)16(28)20-7-1-2-13(27)26-30/h3-6,9,21,30H,1-2,7-8H2,(H,20,28)(H,26,27)(H3,19,22,24,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of His-tagged HDAC6 (unknown origin) expressed in Escherichia coli BL21(DE3) after 60 mins by MALDI mass spectrometry				Eur J Med Chem 96: 340-59 (2015) Article DOI: 10.1016/j.ejmech.2015.04.014 BindingDB Entry DOI: 10.7270/Q269759B
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