BDBM50080448 3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL119013
SMILES: CN1C2CCC1CC(C2)OC(c1ccccc1)c1cccc(Cl)c1
InChI Key: InChIKey=FMPUWHUXNOPVQS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Muscarinic acetylcholine receptor M1 (RAT) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity for muscarinic m1 receptor was determined in vitro in rat brain using [3H]pirenzepine as radioligand. | J Med Chem 44: 633-40 (2001) BindingDB Entry DOI: 10.7270/Q2MP540N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 21.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity for dopamine transporter was determined in vitro in rat brain using [3H]WIN-35428 s radioligand | J Med Chem 44: 633-40 (2001) BindingDB Entry DOI: 10.7270/Q2MP540N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter in rat caudate putamen tissue. | J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 258 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity for serotonin transporter was determined in vitro in rat brain using [3H]citalopram as radioligand. | J Med Chem 44: 633-40 (2001) BindingDB Entry DOI: 10.7270/Q2MP540N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 451 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity for norepinephrine transporter in rat brain using [3H]-nisoxatine as radioligand | J Med Chem 44: 633-40 (2001) BindingDB Entry DOI: 10.7270/Q2MP540N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50080448 (3-[(3-Chloro-phenyl)-phenyl-methoxy]-8-methyl-8-az...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse - Intramural Research Program Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine uptake in rat caudate putamen tissue. | J Med Chem 42: 3502-9 (1999) Article DOI: 10.1021/jm980701v BindingDB Entry DOI: 10.7270/Q2VD705D | |||||||||||
More data for this Ligand-Target Pair |