BDBM50080481 4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-pyridine-2-carboxamidine::CHEMBL333639

SMILES: COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccnc(c2)C(N)=N)C1=O

InChI Key: InChIKey=UPAPPWMUBINJHX-IBGZPJMESA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50080481 (4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccnc(c2)C(N)=N)C1=O Show InChI InChI=1S/C22H23N5O4S/c1-31-17-4-2-15-3-5-18(12-16(15)11-17)32(29,30)26-19-7-9-27(22(19)28)13-14-6-8-25-20(10-14)21(23)24/h2-6,8,10-12,19,26H,7,9,13H2,1H3,(H3,23,24)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human Coagulation factor Xa				J Med Chem 42: 3557-71 (1999) Article DOI: 10.1021/jm990040h BindingDB Entry DOI: 10.7270/Q2M04640
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50080481 (4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccnc(c2)C(N)=N)C1=O Show InChI InChI=1S/C22H23N5O4S/c1-31-17-4-2-15-3-5-18(12-16(15)11-17)32(29,30)26-19-7-9-27(22(19)28)13-14-6-8-25-20(10-14)21(23)24/h2-6,8,10-12,19,26H,7,9,13H2,1H3,(H3,23,24)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibition of human thrombin				J Med Chem 42: 3557-71 (1999) Article DOI: 10.1021/jm990040h BindingDB Entry DOI: 10.7270/Q2M04640
					More data for this Ligand-Target Pair
Trypsin II (Bos taurus)	BDBM50080481 (4-[(S)-3-(7-Methoxy-naphthalene-2-sulfonylamino)-2...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccnc(c2)C(N)=N)C1=O Show InChI InChI=1S/C22H23N5O4S/c1-31-17-4-2-15-3-5-18(12-16(15)11-17)32(29,30)26-19-7-9-27(22(19)28)13-14-6-8-25-20(10-14)21(23)24/h2-6,8,10-12,19,26H,7,9,13H2,1H3,(H3,23,24)/t19-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreatic trypsin				J Med Chem 42: 3557-71 (1999) Article DOI: 10.1021/jm990040h BindingDB Entry DOI: 10.7270/Q2M04640
					More data for this Ligand-Target Pair