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SMILES: CN(C[C@H]1C[C@H](Cc2c[nH]c3ccc(cc23)-n2ccnc2)N(C)C1)Cc1ccccc1

InChI Key: InChIKey=ZXOAWPAKYYSNFI-ZJSXRUAMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080892   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1D


(Homo sapiens (Human))		BDBM50080892
PNG
(Benzyl-[(3R,5R)-5-(5-imidazol-1-yl-1H-indol-3-ylme...)
Show SMILES CN(C[C@H]1C[C@H](Cc2c[nH]c3ccc(cc23)-n2ccnc2)N(C)C1)Cc1ccccc1
Show InChI InChI=1S/C26H31N5/c1-29(16-20-6-4-3-5-7-20)17-21-12-24(30(2)18-21)13-22-15-28-26-9-8-23(14-25(22)26)31-11-10-27-19-31/h3-11,14-15,19,21,24,28H,12-13,16-18H2,1-2H3/t21-,24-/m1/s1
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Similars
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Ability to displace [3H]- -5-HT binding to cloned 5-hydroxytryptamine 1D receptor stably expressed in chinese hamster cells (CHO cells)

Bioorg Med Chem Lett 9: 2491-6 (1999)


BindingDB Entry DOI: 10.7270/Q27M074P
More data for this
Ligand-Target Pair