BDBM50081058 CHEMBL3421842::US10166214, Example 22::US10675268, Example 22::US9789082, Example 22
SMILES: [H][C@@]12CNC[C@]1([H])[C@H]2C(=O)NC(C)(C)c1nc(C)cc2ccccc12
InChI Key: InChIKey=GSKQCADKMBMWTN-ZSHCYNCHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 4 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 848 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 848 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 848 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 1 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 848 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 3 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 2 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description For the binding experiments 200 μL of membrane homogenate from one of the following protein amounts is used: hSSTR1 (40 μg/well); hSSTR2 (2... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | >9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description Receptor binding assays refer to a technique in which labeled receptor ligands are used to detect binding to a receptor. In competition experiments t... | US Patent US9789082 (2017) BindingDB Entry DOI: 10.7270/Q2CN760Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >9.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Displacement of [3-125l-Tyr]-somatostatin-(1 -14) from human recombinant somatostatin 5 receptor expressed in CHO cell membranes incubated for 180 mi... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL | Assay Description Agonist activity at human somatostatin 4 receptor expressed in H4 cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation i... | ACS Med Chem Lett 6: 110-1 (2015) Article DOI: 10.1021/ml500538a BindingDB Entry DOI: 10.7270/Q2MC91RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia... | US Patent US10166214 (2019) BindingDB Entry DOI: 10.7270/Q2D50Q16 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50081058 (CHEMBL3421842 | US10166214, Example 22 | US1067526...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Centrexion Therapeutics Corporation US Patent | Assay Description The activation of the SSTR4 receptor (Gi coupled) causes an inhibition of intracellular cAMP after stimulation with Forskolin, which can be quantifia... | US Patent US10675268 (2020) | |||||||||||
More data for this Ligand-Target Pair |