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BDBM50081163 CHEMBL3421944

SMILES: [#6]-[#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7](-[#6]-c3ccccc3)-[#6](=O)-[#7](-[#6]-c3ccccc3)-[#6]-2=O)cc1-[#8]-[#6]

InChI Key: InChIKey=UDTBYTKDBAJLNK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081163   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone acetyltransferase p300


(Homo sapiens (Human))		BDBM50081163
PNG
(CHEMBL3421944)
Show SMILES [#6]-[#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7](-[#6]-c3ccccc3)-[#6](=O)-[#7](-[#6]-c3ccccc3)-[#6]-2=O)cc1-[#8]-[#6]
Show InChI InChI=1S/C27H24N2O5/c1-33-23-14-13-21(16-24(23)34-2)15-22-25(30)28(17-19-9-5-3-6-10-19)27(32)29(26(22)31)18-20-11-7-4-8-12-20/h3-16H,17-18H2,1-2H3
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MMDB

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.14E+4n/an/an/an/an/an/a



Universit£ degli Studi di Salerno

Curated by ChEMBL


Assay Description
Inhibition of P300 (unknown origin) using histone H3/[acetyl-3H]-acetyl coenzyme A as substrate

J Med Chem 58: 2779-98 (2015)


Article DOI: 10.1021/jm5019687
BindingDB Entry DOI: 10.7270/Q2736SMP
More data for this
Ligand-Target Pair