BDBM50081233 3-[(Z)-ethylidene]-7,11,15-trimethyl-(6E,10E)-1,6,10,14-hexadecatetraene1-diphosphate (3-vGGPP)

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]=[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O

InChI Key: InChIKey=LCLOQXIAVGWVEU-RFRQLJORSA-K

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50081233 (3-[(Z)-ethylidene]-7,11,15-trimethyl-(6E,10E)-1,6,...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]=[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O Show InChI InChI=1S/C21H36O7P2/c1-6-21(16-17-27-30(25,26)28-29(22,23)24)15-9-14-20(5)13-8-12-19(4)11-7-10-18(2)3/h6,10,12,14,16H,1,7-9,11,13,15,17H2,2-5H3,(H,25,26)(H2,22,23,24)/p-3/b19-12+,20-14+,21-16+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assay				J Med Chem 42: 3800-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z89D3S
					More data for this Ligand-Target Pair
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50081233 (3-[(Z)-ethylidene]-7,11,15-trimethyl-(6E,10E)-1,6,...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]=[#6])=[#6]\[#6]-[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O Show InChI InChI=1S/C21H36O7P2/c1-6-21(16-17-27-30(25,26)28-29(22,23)24)15-9-14-20(5)13-8-12-19(4)11-7-10-18(2)3/h6,10,12,14,16H,1,7-9,11,13,15,17H2,2-5H3,(H,25,26)(H2,22,23,24)/p-3/b19-12+,20-14+,21-16+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	715	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assay				J Med Chem 42: 3800-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z89D3S
					More data for this Ligand-Target Pair