BDBM50081637 CHEMBL3422177

SMILES: Nc1nonc1-c1nc2ccccc2n1CC(=O)Nc1ccccc1Cl

InChI Key: InChIKey=WFXICEVOMNRSBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Similar to alpha-tubulin isoform 1 (Bos taurus)	BDBM50081637 (CHEMBL3422177) Show SMILES Nc1nonc1-c1nc2ccccc2n1CC(=O)Nc1ccccc1Cl Show InChI InChI=1S/C17H13ClN6O2/c18-10-5-1-2-6-11(10)20-14(25)9-24-13-8-4-3-7-12(13)21-17(24)15-16(19)23-26-22-15/h1-8H,9H2,(H2,19,23)(H,20,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Special Design and Construction Bureau SDCB"Technolog" Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization by turbidity assay				Eur J Med Chem 94: 237-51 (2015) Article DOI: 10.1016/j.ejmech.2015.02.051 BindingDB Entry DOI: 10.7270/Q2FN17XK
					More data for this Ligand-Target Pair