null

SMILES: C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1

InChI Key: InChIKey=ZHSYVBJQABBSPQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50081747 (4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1 Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-21-16-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2C receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50081747 (4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1 Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-21-16-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 3A (Rattus norvegicus (Rat))	BDBM50081747 (4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...) Show SMILES C(CN1CCC(Cc2ccccc2)CC1)C#Cc1cn[nH]c1 Show InChI InChI=1S/C19H23N3/c1-2-6-17(7-3-1)14-18-9-12-22(13-10-18)11-5-4-8-19-15-20-21-16-19/h1-3,6-7,15-16,18H,5,9-14H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of NMDA response at cloned NR1A/2A receptor expressed in Xenopus oocytes				Bioorg Med Chem Lett 9: 2815-8 (1999) BindingDB Entry DOI: 10.7270/Q2Z037BT
					More data for this Ligand-Target Pair