BDBM50081836 CHEMBL95616::[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-(2-fluoro-phenyl)-acetic acid

SMILES: N[C@@H](Cc1ccc(O)cc1)C(=O)NC(C(O)=O)c1ccccc1F

InChI Key: InChIKey=DULPZMDKLICYRF-MLCCFXAWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-tRNA synthetase (Homo sapiens (Human))	BDBM50081836 (CHEMBL95616 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-pr...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)NC(C(O)=O)c1ccccc1F Show InChI InChI=1S/C17H17FN2O4/c18-13-4-2-1-3-12(13)15(17(23)24)20-16(22)14(19)9-10-5-7-11(21)8-6-10/h1-8,14-15,21H,9,19H2,(H,20,22)(H,23,24)/t14-,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA Synthetase				Bioorg Med Chem Lett 9: 2859-62 (1999) BindingDB Entry DOI: 10.7270/Q2F18XX9
					More data for this Ligand-Target Pair