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BDBM50081995 2-(4-(9-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl)acetic acid::CHEMBL136666::[4-(9-Fluoro-pyrrolo[1,2-a]quinoxalin-4-yl)-piperazin-1-yl]-acetic acid

SMILES: OC(=O)CN1CCN(CC1)c1nc2cccc(F)c2n2cccc12

InChI Key: InChIKey=DQEBWDLUDOIBCJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081995   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50081995
PNG
(2-(4-(9-fluoropyrrolo[1,2-a]quinoxalin-4-yl)pipera...)
Show SMILES OC(=O)CN1CCN(CC1)c1nc2cccc(F)c2n2cccc12
Show InChI InChI=1S/C17H17FN4O2/c18-12-3-1-4-13-16(12)22-6-2-5-14(22)17(19-13)21-9-7-20(8-10-21)11-15(23)24/h1-6H,7-11H2,(H,23,24)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 920n/an/an/an/an/an/a



Universita' degli Studi di Salerno

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligand

J Med Chem 42: 4362-79 (1999)


BindingDB Entry DOI: 10.7270/Q2S75FJM
More data for this
Ligand-Target Pair