BDBM50082199 CH3-CH2-COOH::CHEMBL14021::Propionsaeure::acide propanoique::acide propionique::carboxyethane::ethanecarboxylic acid::ethylformic acid::metacetonic acid::methylacetic acid::propanoic acid::propioic acid::propionic acid::propoic acid::pseudoacetic acid

SMILES: CCC(O)=O

InChI Key: InChIKey=XBDQKXXYIPTUBI-UHFFFAOYSA-N

Data: 2 KI  1 IC50  6 EC50

PDB links: 17 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50082199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 22 member 20 (Mus musculus)	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.82E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
					More data for this Ligand-Target Pair
Solute carrier family 22 member 6 (Mus musculus)	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	8.18E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr				J Biol Chem 282: 23841-53 (2007) Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cell membrane assessed as stimulation of [35S]-GTPgammaS binding meas...				J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Mus musculus)	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol production				J Med Chem 61: 9534-9550 (2018) Article DOI: 10.1021/acs.jmedchem.8b00855 BindingDB Entry DOI: 10.7270/Q28S4SFW
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.57E+5	n/a	n/a	n/a	n/a
Ogeda SA Curated by ChEMBL					Assay Description Agonist activity at human FFA2R expressed in CHOK1 cells assessed as induction of GTPgamma35S binding preincubated for 15 mins followed by GTPgamma35...				Bioorg Med Chem 26: 5169-5180 (2018) Article DOI: 10.1016/j.bmc.2018.09.015 BindingDB Entry DOI: 10.7270/Q2RV0R8R
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human FFA3 receptor stably expressed in Flp-In T-Rex HEK293 cells cotransfected with eYFP assessed as inhibition of forskolin-ind...				J Med Chem 63: 3577-3595 (2020) Article DOI: 10.1021/acs.jmedchem.9b02036
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a
Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy. Curated by ChEMBL					Assay Description Agonist activity at human GPCR43 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method				J Med Chem 61: 47-61 (2018) Article DOI: 10.1021/acs.jmedchem.7b00244 BindingDB Entry DOI: 10.7270/Q2JD507R
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production				Bioorg Med Chem Lett 20: 493-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.112 BindingDB Entry DOI: 10.7270/Q21V5F2Q
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50082199 (CH3-CH2-COOH | CHEMBL14021 | Propionsaeure | acide...) Show SMILES CCC(O)=O Show InChI InChI=1S/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a
Department of Pharmacy and Biotechnology, University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy. Curated by ChEMBL					Assay Description Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method				J Med Chem 61: 47-61 (2018) Article DOI: 10.1021/acs.jmedchem.7b00244 BindingDB Entry DOI: 10.7270/Q2JD507R
					More data for this Ligand-Target Pair