BDBM50082221 (2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)-2-(7-fluoro-naphthalen-2-ylmethyl)-3,N*4*-dihydroxy-succinamide::CHEMBL110713

SMILES: CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2ccc(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O

InChI Key: InChIKey=LZBZUJWYYDTNDA-IXDOHACOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50082221 ((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2ccc(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O Show InChI InChI=1S/C21H26FN3O5/c1-21(2,3)17(18(23)27)24-19(28)15(16(26)20(29)25-30)9-11-4-5-12-6-7-14(22)10-13(12)8-11/h4-8,10,15-17,26,30H,9H2,1-3H3,(H2,23,27)(H,24,28)(H,25,29)/t15-,16+,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against IgE receptor				Bioorg Med Chem Lett 9: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2MK6C37
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50082221 ((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2ccc(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O Show InChI InChI=1S/C21H26FN3O5/c1-21(2,3)17(18(23)27)24-19(28)15(16(26)20(29)25-30)9-11-4-5-12-6-7-14(22)10-13(12)8-11/h4-8,10,15-17,26,30H,9H2,1-3H3,(H2,23,27)(H,24,28)(H,25,29)/t15-,16+,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase(MMP-1)				Bioorg Med Chem Lett 9: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2MK6C37
					More data for this Ligand-Target Pair