null

SMILES: OC1(CCN(CCCC(C#N)c2cccs2)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=CMFKIUAFSUSUDX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50082713 (5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...) Show SMILES OC1(CCN(CCCC(C#N)c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClN2OS/c21-18-7-5-17(6-8-18)20(24)9-12-23(13-10-20)11-1-3-16(15-22)19-4-2-14-25-19/h2,4-8,14,16,24H,1,3,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cells				J Med Chem 42: 4680-94 (1999) BindingDB Entry DOI: 10.7270/Q2125TCC
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50082713 (5-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-2...) Show SMILES OC1(CCN(CCCC(C#N)c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H23ClN2OS/c21-18-7-5-17(6-8-18)20(24)9-12-23(13-10-20)11-1-3-16(15-22)19-4-2-14-25-19/h2,4-8,14,16,24H,1,3,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptor				J Med Chem 42: 4680-94 (1999) BindingDB Entry DOI: 10.7270/Q2125TCC
					More data for this Ligand-Target Pair