BDBM50082836 4,4-Bis-(3,5-dimethyl-phenyl)-piperidine::CHEMBL144894

SMILES: Cc1cc(C)cc(c1)C1(CCNCC1)c1cc(C)cc(C)c1

InChI Key: InChIKey=YPGIWJYVYKQSFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50082836 (4,4-Bis-(3,5-dimethyl-phenyl)-piperidine | CHEMBL1...) Show SMILES Cc1cc(C)cc(c1)C1(CCNCC1)c1cc(C)cc(C)c1 Show InChI InChI=1S/C21H27N/c1-15-9-16(2)12-19(11-15)21(5-7-22-8-6-21)20-13-17(3)10-18(4)14-20/h9-14,22H,5-8H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Opioid receptor mu 1 using [3H]-DAMGO ligand				J Med Chem 42: 4778-93 (1999) BindingDB Entry DOI: 10.7270/Q2930SCW
					More data for this Ligand-Target Pair