BDBM50082906 2-[(5-{[Acetyl-(2-cyclohexyl-ethyl)-amino]-methyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-lithium-butarate::CHEMBL177445

SMILES: CSCC[C@H](NC(=O)c1ccc(CN(CCC2CCCCC2)C(C)=O)cc1-c1ccccc1C)C([O-])=O

InChI Key: InChIKey=CHDWTRUYQSFVEW-NDEPHWFRSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082906   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50082906 (2-[(5-{[Acetyl-(2-cyclohexyl-ethyl)-amino]-methyl}...) Show SMILES CSCC[C@H](NC(=O)c1ccc(CN(CCC2CCCCC2)C(C)=O)cc1-c1ccccc1C)C([O-])=O Show InChI InChI=1S/C30H40N2O4S/c1-21-9-7-8-12-25(21)27-19-24(20-32(22(2)33)17-15-23-10-5-4-6-11-23)13-14-26(27)29(34)31-28(30(35)36)16-18-37-3/h7-9,12-14,19,23,28H,4-6,10-11,15-18,20H2,1-3H3,(H,31,34)(H,35,36)/p-1/t28-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Farnesyltransferase (FTase)				J Med Chem 42: 4844-52 (1999) BindingDB Entry DOI: 10.7270/Q2WW7GWR
					More data for this Ligand-Target Pair