BDBM50082912 (S)-2-({5-[((S)-1-Cyclohexyl-2-hydroxy-ethylamino)-methyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid::CHEMBL424119

SMILES: CSCC[C@H](NC(=O)c1ccc(CN[C@H](CO)C2CCCCC2)cc1-c1ccccc1C)C(O)=O

InChI Key: InChIKey=ZPNGKLKMBATBLI-IZZNHLLZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50082912 ((S)-2-({5-[((S)-1-Cyclohexyl-2-hydroxy-ethylamino)...) Show SMILES CSCC[C@H](NC(=O)c1ccc(CN[C@H](CO)C2CCCCC2)cc1-c1ccccc1C)C(O)=O Show InChI InChI=1S/C28H38N2O4S/c1-19-8-6-7-11-22(19)24-16-20(17-29-26(18-31)21-9-4-3-5-10-21)12-13-23(24)27(32)30-25(28(33)34)14-15-35-2/h6-8,11-13,16,21,25-26,29,31H,3-5,9-10,14-15,17-18H2,1-2H3,(H,30,32)(H,33,34)/t25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Farnesyltransferase (FTase)				J Med Chem 42: 4844-52 (1999) BindingDB Entry DOI: 10.7270/Q2WW7GWR
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