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SMILES: CSCC[C@H](NC(=O)c1ccc(CN[C@H](CO)Cc2ccccc2)cc1-c1ccccc1C)C(O)=O

InChI Key: InChIKey=GYOPLKVPTMXBCN-HOFKKMOUSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082916   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Rattus norvegicus-Rattus norvegicus (rat))		BDBM50082916
PNG
((S)-2-({5-[((S)-1-Hydroxymethyl-2-phenyl-ethylamin...)
Show SMILES CSCC[C@H](NC(=O)c1ccc(CN[C@H](CO)Cc2ccccc2)cc1-c1ccccc1C)C(O)=O
Show InChI InChI=1S/C29H34N2O4S/c1-20-8-6-7-11-24(20)26-17-22(18-30-23(19-32)16-21-9-4-3-5-10-21)12-13-25(26)28(33)31-27(29(34)35)14-15-36-2/h3-13,17,23,27,30,32H,14-16,18-19H2,1-2H3,(H,31,33)(H,34,35)/t23-,27-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 4.60n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Farnesyltransferase (FTase)

J Med Chem 42: 4844-52 (1999)


BindingDB Entry DOI: 10.7270/Q2WW7GWR
More data for this
Ligand-Target Pair