BDBM50083153 2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-[1,4']bipiperidinyl::CHEMBL147838

SMILES: C(CN1CCC(CC1)N1CCCCC1c1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key: InChIKey=WGWBIIDCWJHIOA-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50083153 (2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...) Show SMILES C(CN1CCC(CC1)N1CCCCC1c1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C29H36N6/c1-2-7-23(8-3-1)29-10-4-5-16-35(29)25-13-17-33(18-14-25)15-6-9-24-20-30-28-12-11-26(19-27(24)28)34-21-31-32-22-34/h1-3,7-8,11-12,19-22,25,29-30H,4-6,9-10,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cells				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50083153 (2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...) Show SMILES C(CN1CCC(CC1)N1CCCCC1c1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C29H36N6/c1-2-7-23(8-3-1)29-10-4-5-16-35(29)25-13-17-33(18-14-25)15-6-9-24-20-30-28-12-11-26(19-27(24)28)34-21-31-32-22-34/h1-3,7-8,11-12,19-22,25,29-30H,4-6,9-10,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cells				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50083153 (2-Phenyl-1'-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-y...) Show SMILES C(CN1CCC(CC1)N1CCCCC1c1ccccc1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C29H36N6/c1-2-7-23(8-3-1)29-10-4-5-16-35(29)25-13-17-33(18-14-25)15-6-9-24-20-30-28-12-11-26(19-27(24)28)34-21-31-32-22-34/h1-3,7-8,11-12,19-22,25,29-30H,4-6,9-10,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptor				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair