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SMILES: COc1ccccc1N1CCN(CCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1

InChI Key: InChIKey=ISWDMNVHBNKXAZ-GUHGBLDKSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083292   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50083292
PNG
(1-Adamantan-1-yl-3-{2-[4-(2-methoxy-phenyl)-pipera...)
Show SMILES COc1ccccc1N1CCN(CCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 |TLB:25:24:27:20.19.21,25:20:27:24.26.23,17:18:23:20.21.25,THB:17:18:21:24.23.25,26:18:21:24.23.25,19:18:23:20.21.25|
Show InChI InChI=1S/C24H36N4O2/c1-30-22-5-3-2-4-21(22)28-10-8-27(9-11-28)7-6-25-23(29)26-24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H2,25,26,29)/t18-,19+,20-,24?
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 9n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor

J Med Chem 42: 5077-94 (2000)


BindingDB Entry DOI: 10.7270/Q2C82B0P
More data for this
Ligand-Target Pair