BDBM50083335 6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxazin-3-one::CHEMBL147130

SMILES: O=C1COc2ccc(CN3CCN(CC3)c3ccccc3)cc2N1

InChI Key: InChIKey=NFRIERLNKMVOKN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50083335 (6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxa...) Show SMILES O=C1COc2ccc(CN3CCN(CC3)c3ccccc3)cc2N1 Show InChI InChI=1S/C19H21N3O2/c23-19-14-24-18-7-6-15(12-17(18)20-19)13-21-8-10-22(11-9-21)16-4-2-1-3-5-16/h1-7,12H,8-11,13-14H2,(H,20,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D4 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50083335 (6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxa...) Show SMILES O=C1COc2ccc(CN3CCN(CC3)c3ccccc3)cc2N1 Show InChI InChI=1S/C19H21N3O2/c23-19-14-24-18-7-6-15(12-17(18)20-19)13-21-8-10-22(11-9-21)16-4-2-1-3-5-16/h1-7,12H,8-11,13-14H2,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	839	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D3 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50083335 (6-(4-Phenyl-piperazin-1-ylmethyl)-4H-benzo[1,4]oxa...) Show SMILES O=C1COc2ccc(CN3CCN(CC3)c3ccccc3)cc2N1 Show InChI InChI=1S/C19H21N3O2/c23-19-14-24-18-7-6-15(12-17(18)20-19)13-21-8-10-22(11-9-21)16-4-2-1-3-5-16/h1-7,12H,8-11,13-14H2,(H,20,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity at Dopamine receptor D2 in CHO cells by radioligand displacement.				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
					More data for this Ligand-Target Pair