BDBM50083360 CHEMBL3423330

SMILES: Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCCN1CCN(CC1)c1ccccc1O

InChI Key: InChIKey=YJXDJZLDWYWBPH-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083360 (CHEMBL3423330) Show SMILES Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCCN1CCN(CC1)c1ccccc1O Show InChI InChI=1S/C24H31N7O3/c1-17-16-31-20-21(26(2)24(34)27(3)22(20)33)25-23(31)30(17)11-7-6-10-28-12-14-29(15-13-28)18-8-4-5-9-19(18)32/h4-5,8-9,16,32H,6-7,10-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat hippocampus 5-HT1A receptor incubated for 20 mins by microbeta plate reader based method				Eur J Med Chem 97: 142-54 (2015) Article DOI: 10.1016/j.ejmech.2015.04.046 BindingDB Entry DOI: 10.7270/Q2TQ637Z
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50083360 (CHEMBL3423330) Show SMILES Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCCN1CCN(CC1)c1ccccc1O Show InChI InChI=1S/C24H31N7O3/c1-17-16-31-20-21(26(2)24(34)27(3)22(20)33)25-23(31)30(17)11-7-6-10-28-12-14-29(15-13-28)18-8-4-5-9-19(18)32/h4-5,8-9,16,32H,6-7,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor expressed in CHOK1 cells incubated for 60 mins by microbeta plate r...				Eur J Med Chem 97: 142-54 (2015) Article DOI: 10.1016/j.ejmech.2015.04.046 BindingDB Entry DOI: 10.7270/Q2TQ637Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50083360 (CHEMBL3423330) Show SMILES Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCCN1CCN(CC1)c1ccccc1O Show InChI InChI=1S/C24H31N7O3/c1-17-16-31-20-21(26(2)24(34)27(3)22(20)33)25-23(31)30(17)11-7-6-10-28-12-14-29(15-13-28)18-8-4-5-9-19(18)32/h4-5,8-9,16,32H,6-7,10-15H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human recombinant 5-HT7 receptor expressed in CHOK1 cells incubated for 60 mins by microbeta plate reader based method				Eur J Med Chem 97: 142-54 (2015) Article DOI: 10.1016/j.ejmech.2015.04.046 BindingDB Entry DOI: 10.7270/Q2TQ637Z
					More data for this Ligand-Target Pair