BDBM50083929 CHEMBL3423204

SMILES: COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)Cc1cccc(Oc2ccccc2)c1)C(C)C)[C@H](C)O

InChI Key: InChIKey=IGHWCJWROTUTBX-MDGXYFOHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50083929 (CHEMBL3423204) Show SMILES COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)Cc1cccc(Oc2ccccc2)c1)C(C)C)[C@H](C)O |r| Show InChI InChI=1S/C28H36N4O8/c1-16(2)24(27(37)32-25(17(3)33)28(38)39-4)31-26(36)21(15-22(29)34)30-23(35)14-18-9-8-12-20(13-18)40-19-10-6-5-7-11-19/h5-13,16-17,21,24-25,33H,14-15H2,1-4H3,(H2,29,34)(H,30,35)(H,31,36)(H,32,37)/t17-,21-,24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human beta-5 subunit of 20S proteasome using Suc-LLVY-AMC as substrate by fluorometer analysis				Eur J Med Chem 98: 61-8 (2015) Article DOI: 10.1016/j.ejmech.2015.05.023 BindingDB Entry DOI: 10.7270/Q228099R
					More data for this Ligand-Target Pair