BDBM50084337 CHEMBL67078::[1-(2-Benzhydryloxy-ethyl)-piperidin-3-ylmethyl]-(3-phenyl-propyl)-amine

SMILES: C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1

InChI Key: InChIKey=FDTFUBJUWHYSGU-UHFFFAOYSA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Binding affinity at the norepinephrine transporter was measured using [125I]RTI-55 as a radioligand				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to dopamine transporter				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Binding affinity for serotonin transporter using [125I]RTI-55				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine reuptake in HEK293 cells expressing human dopamine transporter				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT reuptake in HEK293 cells expressing human serotonin transporter				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50084337 (CHEMBL67078 | [1-(2-Benzhydryloxy-ethyl)-piperidin...) Show SMILES C(CNCC1CCCN(CCOC(c2ccccc2)c2ccccc2)C1)Cc1ccccc1 Show InChI InChI=1S/C30H38N2O/c1-4-12-26(13-5-1)14-10-20-31-24-27-15-11-21-32(25-27)22-23-33-30(28-16-6-2-7-17-28)29-18-8-3-9-19-29/h1-9,12-13,16-19,27,30-31H,10-11,14-15,20-25H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Massachusetts General Hospital Curated by ChEMBL					Assay Description Inhibition of [3H]NE reuptake by human norepinephrine transporter expressed in HEK293 cells				J Med Chem 43: 205-13 (2000) BindingDB Entry DOI: 10.7270/Q2JH3MW0
					More data for this Ligand-Target Pair