null

SMILES: NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1

InChI Key: InChIKey=RPTFKXDBRBKHQU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084365 (4-(2-Oxo-3-phenyl-2,3-dihydro-oxazol-4-yl)-benzene...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1 Show InChI InChI=1S/C15H12N2O4S/c16-22(19,20)13-8-6-11(7-9-13)14-10-21-15(18)17(14)12-4-2-1-3-5-12/h1-10H,(H2,16,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 1				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084365 (4-(2-Oxo-3-phenyl-2,3-dihydro-oxazol-4-yl)-benzene...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1 Show InChI InChI=1S/C15H12N2O4S/c16-22(19,20)13-8-6-11(7-9-13)14-10-21-15(18)17(14)12-4-2-1-3-5-12/h1-10H,(H2,16,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 1				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084365 (4-(2-Oxo-3-phenyl-2,3-dihydro-oxazol-4-yl)-benzene...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1 Show InChI InChI=1S/C15H12N2O4S/c16-22(19,20)13-8-6-11(7-9-13)14-10-21-15(18)17(14)12-4-2-1-3-5-12/h1-10H,(H2,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084365 (4-(2-Oxo-3-phenyl-2,3-dihydro-oxazol-4-yl)-benzene...) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1coc(=O)n1-c1ccccc1 Show InChI InChI=1S/C15H12N2O4S/c16-22(19,20)13-8-6-11(7-9-13)14-10-21-15(18)17(14)12-4-2-1-3-5-12/h1-10H,(H2,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 2				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair