null

SMILES: Cc1oc(=O)n(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(C)cc1

InChI Key: InChIKey=JAPKJIUHTVTGNM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084367   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084367 (4-(5-Methyl-2-oxo-3-p-tolyl-2,3-dihydro-oxazol-4-y...) Show SMILES Cc1oc(=O)n(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(C)cc1 Show InChI InChI=1S/C17H16N2O4S/c1-11-3-7-14(8-4-11)19-16(12(2)23-17(19)20)13-5-9-15(10-6-13)24(18,21)22/h3-10H,1-2H3,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 2				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084367 (4-(5-Methyl-2-oxo-3-p-tolyl-2,3-dihydro-oxazol-4-y...) Show SMILES Cc1oc(=O)n(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(C)cc1 Show InChI InChI=1S/C17H16N2O4S/c1-11-3-7-14(8-4-11)19-16(12(2)23-17(19)20)13-5-9-15(10-6-13)24(18,21)22/h3-10H,1-2H3,(H2,18,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 1				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50084367 (4-(5-Methyl-2-oxo-3-p-tolyl-2,3-dihydro-oxazol-4-y...) Show SMILES Cc1oc(=O)n(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(C)cc1 Show InChI InChI=1S/C17H16N2O4S/c1-11-3-7-14(8-4-11)19-16(12(2)23-17(19)20)13-5-9-15(10-6-13)24(18,21)22/h3-10H,1-2H3,(H2,18,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Binding affinity towards Prostaglandin G/H synthase 2				Bioorg Med Chem Lett 13: 3753-7 (2003) BindingDB Entry DOI: 10.7270/Q2JM2BS0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50084367 (4-(5-Methyl-2-oxo-3-p-tolyl-2,3-dihydro-oxazol-4-y...) Show SMILES Cc1oc(=O)n(c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(C)cc1 Show InChI InChI=1S/C17H16N2O4S/c1-11-3-7-14(8-4-11)19-16(12(2)23-17(19)20)13-5-9-15(10-6-13)24(18,21)22/h3-10H,1-2H3,(H2,18,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 1				J Med Chem 43: 214-23 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KK0
					More data for this Ligand-Target Pair