BDBM50084735 1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazine-1-carbonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL338223

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1

InChI Key: InChIKey=VPTHOUBPDJAAER-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50084735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Binding affinity towards matrix metalloprotease-3				J Med Chem 44: 3849-55 (2001) BindingDB Entry DOI: 10.7270/Q2ZK5HWX
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	354	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human))	BDBM50084735 (1-(4-Methoxy-benzenesulfonyl)-4-(4-methyl-piperazi...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)N1CCN(C)CC1 Show InChI InChI=1S/C18H27N5O6S/c1-20-7-9-21(10-8-20)18(25)22-11-12-23(16(13-22)17(24)19-26)30(27,28)15-5-3-14(29-2)4-6-15/h3-6,16,26H,7-13H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair