null

SMILES: COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1

InChI Key: InChIKey=WQCOVODIHQDZNG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50084736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
University of Missouri-St. Louis Curated by ChEMBL					Assay Description Binding affinity towards matrix metalloprotease-3				J Med Chem 44: 3849-55 (2001) BindingDB Entry DOI: 10.7270/Q2ZK5HWX
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50084736 (1-(4-Methoxy-benzenesulfonyl)-4-(5-methyl-3-phenyl...) Show SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1c(C)onc1-c1ccccc1 Show InChI InChI=1S/C23H24N4O7S/c1-15-20(21(25-34-15)16-6-4-3-5-7-16)23(29)26-12-13-27(19(14-26)22(28)24-30)35(31,32)18-10-8-17(33-2)9-11-18/h3-11,19,30H,12-14H2,1-2H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13)				J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3
					More data for this Ligand-Target Pair