BDBM50084758 3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid 3-ethoxy-propyl ester::CHEMBL333586
SMILES: CCOCCCOC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OC)cc1
InChI Key: InChIKey=QYFKTMNLZHLRIH-UHFFFAOYSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloprotease-9 (MMP-9) | J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloprotease-13 (MMP-13) | J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri-St. Louis Curated by ChEMBL | Assay Description Binding affinity towards matrix metalloprotease-3 | J Med Chem 44: 3849-55 (2001) BindingDB Entry DOI: 10.7270/Q2ZK5HWX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 483 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloprotease-7 (MMP-7) | J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloprotease-1 (MMP-1) | J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50084758 (3-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description In vitro inhibitory activity against matrix metalloprotease-3 (MMP-3) | J Med Chem 43: 369-80 (2000) BindingDB Entry DOI: 10.7270/Q2J965M3 | |||||||||||
More data for this Ligand-Target Pair |