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BDBM50084819 4-(2-{[7-(Quinolin-2-ylmethoxy)-chroman-2-carbonyl]-amino}-ethyl)-benzoic acid::CHEMBL128548

SMILES: OC(=O)c1ccc(CCNC(=O)C2CCc3ccc(OCc4ccc5ccccc5n4)cc3O2)cc1

InChI Key: InChIKey=PWNUXYDNWCWJTG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50084819   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteinyl leukotriene receptor 1


(GUINEA PIG)		BDBM50084819
PNG
(4-(2-{[7-(Quinolin-2-ylmethoxy)-chroman-2-carbonyl...)
Show SMILES OC(=O)c1ccc(CCNC(=O)C2CCc3ccc(OCc4ccc5ccccc5n4)cc3O2)cc1
Show InChI InChI=1S/C29H26N2O5/c32-28(30-16-15-19-5-7-22(8-6-19)29(33)34)26-14-11-21-10-13-24(17-27(21)36-26)35-18-23-12-9-20-3-1-2-4-25(20)31-23/h1-10,12-13,17,26H,11,14-16,18H2,(H,30,32)(H,33,34)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
PubMed
 237n/an/an/an/an/an/an/an/a



Laboratorios Menarini

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes

J Med Chem 43: 392-400 (2000)


BindingDB Entry DOI: 10.7270/Q2DJ5DVX
More data for this
Ligand-Target Pair