BDBM50084826 2,5,7-Trinitro-9-oxo-9H-fluorene-4-carboxylic acid amide::CHEMBL133894

SMILES: NC(=O)c1cc(cc2C(=O)c3cc(cc(c3-c12)[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O

InChI Key: InChIKey=FXCNNLGCNUONLQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50084826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50084826 (2,5,7-Trinitro-9-oxo-9H-fluorene-4-carboxylic acid...) Show SMILES NC(=O)c1cc(cc2C(=O)c3cc(cc(c3-c12)[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C14H6N4O8/c15-14(20)9-3-5(16(21)22)1-7-11(9)12-8(13(7)19)2-6(17(23)24)4-10(12)18(25)26/h1-4H,(H2,15,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Medical School and Mayo Clinic Curated by ChEMBL					Assay Description In vitro inhibition of Farnesyltransferase (FT) by using FT [3H]-SPA kit.				J Med Chem 43: 401-8 (2000) BindingDB Entry DOI: 10.7270/Q28W3F0K
					More data for this Ligand-Target Pair