BDBM50084891 3-Dibenzofuran-3-yl-2-(1-phosphono-3-quinolin-8-yl-propylamino)-propionic acid::CHEMBL359024

SMILES: OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NC(CCc1cccc2cccnc12)P(O)(O)=O

InChI Key: InChIKey=AVFZYNJSZQOSLL-XADRRFQNSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50084891 (3-Dibenzofuran-3-yl-2-(1-phosphono-3-quinolin-8-yl...) Show SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NC(CCc1cccc2cccnc12)P(O)(O)=O Show InChI InChI=1S/C27H25N2O6P/c30-27(31)22(15-17-10-12-21-20-8-1-2-9-23(20)35-24(21)16-17)29-25(36(32,33)34)13-11-19-6-3-5-18-7-4-14-28-26(18)19/h1-10,12,14,16,22,25,29H,11,13,15H2,(H,30,31)(H2,32,33,34)/t22-,25?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase				J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR
					More data for this Ligand-Target Pair
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50084891 (3-Dibenzofuran-3-yl-2-(1-phosphono-3-quinolin-8-yl...) Show SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NC(CCc1cccc2cccnc12)P(O)(O)=O Show InChI InChI=1S/C27H25N2O6P/c30-27(31)22(15-17-10-12-21-20-8-1-2-9-23(20)35-24(21)16-17)29-25(36(32,33)34)13-11-19-6-3-5-18-7-4-14-28-26(18)19/h1-10,12,14,16,22,25,29H,11,13,15H2,(H,30,31)(H2,32,33,34)/t22-,25?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description In vitro inhibition of rat neutral endopeptidase				J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50084891 (3-Dibenzofuran-3-yl-2-(1-phosphono-3-quinolin-8-yl...) Show SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NC(CCc1cccc2cccnc12)P(O)(O)=O Show InChI InChI=1S/C27H25N2O6P/c30-27(31)22(15-17-10-12-21-20-8-1-2-9-23(20)35-24(21)16-17)29-25(36(32,33)34)13-11-19-6-3-5-18-7-4-14-28-26(18)19/h1-10,12,14,16,22,25,29H,11,13,15H2,(H,30,31)(H2,32,33,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description In Vitro inhibition of recombinant human endothelin converting enzyme-1				J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR
					More data for this Ligand-Target Pair
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50084891 (3-Dibenzofuran-3-yl-2-(1-phosphono-3-quinolin-8-yl...) Show SMILES OC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NC(CCc1cccc2cccnc12)P(O)(O)=O Show InChI InChI=1S/C27H25N2O6P/c30-27(31)22(15-17-10-12-21-20-8-1-2-9-23(20)35-24(21)16-17)29-25(36(32,33)34)13-11-19-6-3-5-18-7-4-14-28-26(18)19/h1-10,12,14,16,22,25,29H,11,13,15H2,(H,30,31)(H2,32,33,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description In Vitro inhibition of recombinant human endothelin converting enzyme-1				J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR
					More data for this Ligand-Target Pair