BDBM50084898 2-[3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-propionylamino]-4-methyl-pentanoic acid::CHEMBL357226
SMILES: CC(C)CC(NC(=O)[C@H](Cc1ccc2c(c1)oc1ccccc21)NCP(O)(O)=O)C(O)=O
InChI Key: InChIKey=UGKGUEDVMKIJFU-ZENAZSQFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human)) | BDBM50084898 (2-[3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-p...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In Vitro inhibition of recombinant human endothelin converting enzyme-1 | J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat)) | BDBM50084898 (2-[3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for Biomedical Research Curated by ChEMBL | Assay Description In vitro inhibition of rat neutral endopeptidase | J Med Chem 43: 488-504 (2000) BindingDB Entry DOI: 10.7270/Q21G0MZR | |||||||||||
More data for this Ligand-Target Pair |