BDBM50085036 4-Cyclopropylethynyl-5,6-difluoro-4-trifluoromethyl-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL299935

SMILES: Fc1ccc2NS(=O)(=O)NC(C#CC3CC3)(c2c1F)C(F)(F)F

InChI Key: InChIKey=XFLTZZDQDDBAMD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50085036 (4-Cyclopropylethynyl-5,6-difluoro-4-trifluoromethy...) Show SMILES Fc1ccc2NS(=O)(=O)NC(C#CC3CC3)(c2c1F)C(F)(F)F Show InChI InChI=1S/C13H9F5N2O2S/c14-8-3-4-9-10(11(8)15)12(13(16,17)18,6-5-7-1-2-7)20-23(21,22)19-9/h3-4,7,19-20H,1-2H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH
					More data for this Ligand-Target Pair