BDBM50085273 CHEMBL163396::Phenyl-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-methanone
SMILES: O=C(c1ccccc1)c1ccc(OCCN2CCCC2)cc1
InChI Key: InChIKey=VRZKEEUKXJSGLE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leukotriene A4 hydrolase (Homo sapiens (Human)) | BDBM50085273 (CHEMBL163396 | Phenyl-[4-(2-pyrrolidin-1-yl-ethoxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase | J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ | |||||||||||
More data for this Ligand-Target Pair |