BDBM50085318 CHEMBL3427648

SMILES: ONC(=O)\C=C\c1cccn(Cc2ccc3ccccc3n2)c1=O

InChI Key: InChIKey=YBKZELQGYALNID-CSKARUKUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50085318 (CHEMBL3427648) Show SMILES ONC(=O)\C=C\c1cccn(Cc2ccc3ccccc3n2)c1=O Show InChI InChI=1S/C18H15N3O3/c22-17(20-24)10-8-14-5-3-11-21(18(14)23)12-15-9-7-13-4-1-2-6-16(13)19-15/h1-11,24H,12H2,(H,20,22)/b10-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell nuclear extract using Fluor de Lys as substrate incubated with compound for 30 mins by microtiter-plate reading...				J Med Chem 58: 3512-21 (2015) Article DOI: 10.1021/acs.jmedchem.5b00062 BindingDB Entry DOI: 10.7270/Q2GB25R3
					More data for this Ligand-Target Pair