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Enter Data

BDBM50085346 CHEMBL294290::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-(3,4-dichloro-phenyl)-propionamide

SMILES: ClCC(=O)[C@H](Cc1ccccc1)NC(=O)CCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=QLOZGTZEJDNWFT-KRWDZBQOSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085346
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50085346 (CHEMBL294290 \| N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against alpha-chymotrypsin(alpha-CT)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
Kyoto Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic elastase (Sus scrofa)	BDBM50085346 (CHEMBL294290 \| N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES Show InChI	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
Kyoto Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50085346 (CHEMBL294290 \| N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic trypsin (TRP)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
Kyoto Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50085346 (CHEMBL294290 \| N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte cathepsin G				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
Kyoto Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50085346 (CHEMBL294290 \| N-((S)-1-Benzyl-3-chloro-2-oxo-prop...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human serine protease chymase				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
Kyoto Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair