BDBM50085362 CHEMBL64494::N-((S)-1-Benzyl-3-chloro-2-oxo-propyl)-3-phenyl-acrylamide

SMILES: ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1

InChI Key: InChIKey=FYIDHFRPPMSWNW-FLVLSHQESA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50085362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50085362 (CHEMBL64494 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H18ClNO2/c20-14-18(22)17(13-16-9-5-2-6-10-16)21-19(23)12-11-15-7-3-1-4-8-15/h1-12,17H,13-14H2,(H,21,23)/b12-11+/t17-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic elastase (PPE)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50085362 (CHEMBL64494 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H18ClNO2/c20-14-18(22)17(13-16-9-5-2-6-10-16)21-19(23)12-11-15-7-3-1-4-8-15/h1-12,17H,13-14H2,(H,21,23)/b12-11+/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against alpha-chymotrypsin(alpha-CT)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50085362 (CHEMBL64494 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H18ClNO2/c20-14-18(22)17(13-16-9-5-2-6-10-16)21-19(23)12-11-15-7-3-1-4-8-15/h1-12,17H,13-14H2,(H,21,23)/b12-11+/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte cathepsin G				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair
Chymase (Homo sapiens (Human))	BDBM50085362 (CHEMBL64494 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H18ClNO2/c20-14-18(22)17(13-16-9-5-2-6-10-16)21-19(23)12-11-15-7-3-1-4-8-15/h1-12,17H,13-14H2,(H,21,23)/b12-11+/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against human serine protease chymase				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM50085362 (CHEMBL64494 | N-((S)-1-Benzyl-3-chloro-2-oxo-propy...) Show SMILES ClCC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C19H18ClNO2/c20-14-18(22)17(13-16-9-5-2-6-10-16)21-19(23)12-11-15-7-3-1-4-8-15/h1-12,17H,13-14H2,(H,21,23)/b12-11+/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic trypsin (TRP)				Bioorg Med Chem Lett 10: 199-201 (2000) BindingDB Entry DOI: 10.7270/Q2VM4BGH
					More data for this Ligand-Target Pair