BDBM50085458 (S)-2-{(S)-2-[3-(Acetyl-hydroxy-amino)-2-benzyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid::CHEMBL88228

SMILES: CC(C)C[C@H](NC(=O)C(CN(O)C(C)=O)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key: InChIKey=PANROGYPWFDFRW-VYCPFJESSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral Endopeptidase (NEP) (Rattus norvegicus (Rat))	BDBM50085458 ((S)-2-{(S)-2-[3-(Acetyl-hydroxy-amino)-2-benzyl-pr...) Show SMILES CC(C)C[C@H](NC(=O)C(CN(O)C(C)=O)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C27H35N3O6/c1-18(2)14-23(26(33)29-24(27(34)35)16-21-12-8-5-9-13-21)28-25(32)22(17-30(36)19(3)31)15-20-10-6-4-7-11-20/h4-13,18,22-24,36H,14-17H2,1-3H3,(H,28,32)(H,29,33)(H,34,35)/t22?,23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Neutral endopeptidase				Bioorg Med Chem Lett 10: 257-60 (2000) BindingDB Entry DOI: 10.7270/Q2BK1BJ8
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50085458 ((S)-2-{(S)-2-[3-(Acetyl-hydroxy-amino)-2-benzyl-pr...) Show SMILES CC(C)C[C@H](NC(=O)C(CN(O)C(C)=O)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C27H35N3O6/c1-18(2)14-23(26(33)29-24(27(34)35)16-21-12-8-5-9-13-21)28-25(32)22(17-30(36)19(3)31)15-20-10-6-4-7-11-20/h4-13,18,22-24,36H,14-17H2,1-3H3,(H,28,32)(H,29,33)(H,34,35)/t22?,23-,24-/m0/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of Angiotensin I converting enzyme				Bioorg Med Chem Lett 10: 257-60 (2000) BindingDB Entry DOI: 10.7270/Q2BK1BJ8
					More data for this Ligand-Target Pair