BDBM50085603 CHEMBL3425541

SMILES: Cc1nc2ncccc2n2c(nnc12)-c1ccccc1Cl

InChI Key: InChIKey=OWYZIKSYYVSDHO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50085603 (CHEMBL3425541) Show SMILES Cc1nc2ncccc2n2c(nnc12)-c1ccccc1Cl Show InChI InChI=1S/C15H10ClN5/c1-9-14-19-20-15(10-5-2-3-6-11(10)16)21(14)12-7-4-8-17-13(12)18-9/h2-8H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Inhibition of 6-His-tagged human recombinant PDE2A expressed in Sf9 cells using [3H]cGMP incubated for 40 mins by scintillation proximity assay				ACS Med Chem Lett 6: 282-6 (2015) Article DOI: 10.1021/ml500463t BindingDB Entry DOI: 10.7270/Q2319XMJ
					More data for this Ligand-Target Pair