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BDBM50085817 CHEMBL352881::Phosphoric acid mono-[5-(2-chloro-6-methylamino-purin-9-yl)-2-phosphonooxymethyl-tetrahydro-pyran-3-yl] ester

SMILES: CNc1nc(Cl)nc2n(cnc12)C1COC(COP(O)(O)=O)C(C1)OP(O)(O)=O

InChI Key: InChIKey=NOPLFWLKJAVVPL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085817   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 1


(Meleagris gallopavo)		BDBM50085817
PNG
(CHEMBL352881 | Phosphoric acid mono-[5-(2-chloro-6...)
Show SMILES CNc1nc(Cl)nc2n(cnc12)C1COC(COP(O)(O)=O)C(C1)OP(O)(O)=O
Show InChI InChI=1S/C12H18ClN5O9P2/c1-14-10-9-11(17-12(13)16-10)18(5-15-9)6-2-7(27-29(22,23)24)8(25-3-6)4-26-28(19,20)21/h5-8H,2-4H2,1H3,(H,14,16,17)(H2,19,20,21)(H2,22,23,24)
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 566n/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Inhibition of 30 nM 2-MeSADP stimulation of 2PY1-mediated phospholipase C (PLC) activity in Turkey erythocyte ghosts

J Med Chem 43: 829-42 (2000)


BindingDB Entry DOI: 10.7270/Q2474BJ3
More data for this
Ligand-Target Pair