BDBM50085927 4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-phenol::CHEMBL177620

SMILES: OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1

InChI Key: InChIKey=XLCDZDPSIMQWPV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50085927 (4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...) Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1 Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]-raclopride binding at Dopamine receptor D2 in rat brain membranes.				J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50085927 (4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...) Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1 Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.				J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50085927 (4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...) Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1 Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2C) Receptor subtype.				J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50085927 (4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...) Show SMILES OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1 Show InChI InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2A) Receptor subtype.				J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT
					More data for this Ligand-Target Pair