BDBM50086366 3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-(3-phenyl-propyl)-propionamide::CHEMBL347750

SMILES: CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCCc1ccccc1

InChI Key: InChIKey=AHTQSMPGKJEFNT-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50086366 (3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...) Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of [3H]U-69,593 binding to human Opioid receptor kappa 1 expressed in HEK 293 cells				Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50086366 (3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...) Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1				Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50086366 (3-(3-Hydroxy-phenyl)-2,2-dimethyl-3-methylamino-N-...) Show SMILES CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C21H28N2O2/c1-21(2,19(22-3)17-12-7-13-18(24)15-17)20(25)23-14-8-11-16-9-5-4-6-10-16/h4-7,9-10,12-13,15,19,22,24H,8,11,14H2,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of [3H]-naltrindole binding to human Opioid receptor delta 1 in CHO cells				Bioorg Med Chem Lett 10: 523-6 (2000) BindingDB Entry DOI: 10.7270/Q2BG2N79
					More data for this Ligand-Target Pair