BDBM50087115 1-{[3-Biphenyl-4-yl-2-(1-carboxy-2-phenyl-ethylcarbamoyl)-propyl]-hydroxy-phosphinoyl}-2-phenyl-ethyl-ammonium

SMILES: [NH3+]C(Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key: InChIKey=JDHXZXXLCOKDRZ-AWZUCMKVSA-O

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50087115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Sus scrofa (Pig))	BDBM50087115 (1-{[3-Biphenyl-4-yl-2-(1-carboxy-2-phenyl-ethylcar...) Show SMILES [NH3+]C(Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C33H35N2O5P/c34-31(22-25-12-6-2-7-13-25)41(39,40)23-29(20-26-16-18-28(19-17-26)27-14-8-3-9-15-27)32(36)35-30(33(37)38)21-24-10-4-1-5-11-24/h1-19,29-31H,20-23,34H2,(H,35,36)(H,37,38)(H,39,40)/p+1/t29-,30+,31?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity on aminopeptidase N (APN) using Ala-pNA as substrate.				J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50087115 (1-{[3-Biphenyl-4-yl-2-(1-carboxy-2-phenyl-ethylcar...) Show SMILES [NH3+]C(Cc1ccccc1)P(O)(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O Show InChI InChI=1S/C33H35N2O5P/c34-31(22-25-12-6-2-7-13-25)41(39,40)23-29(20-26-16-18-28(19-17-26)27-14-8-3-9-15-27)32(36)35-30(33(37)38)21-24-10-4-1-5-11-24/h1-19,29-31H,20-23,34H2,(H,35,36)(H,37,38)(H,39,40)/p+1/t29-,30+,31?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibitory activity on neutral endopeptidase (NEP) using DGNPA as substrate.				J Med Chem 43: 1398-408 (2001) BindingDB Entry DOI: 10.7270/Q2TQ627J
					More data for this Ligand-Target Pair