BDBM50087188 (S)-2-(2-Chloro-pyridine-3-carbonyl)-6,8-diiodo-7-(3-trifluoromethyl-benzyloxy)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL349332

SMILES: OC(=O)[C@@H]1Cc2cc(I)c(OCc3cccc(c3)C(F)(F)F)c(I)c2CN1C(=O)c1cccnc1Cl

InChI Key: InChIKey=SAPKKUZJCSCHBQ-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50087188 ((S)-2-(2-Chloro-pyridine-3-carbonyl)-6,8-diiodo-7-...) Show SMILES OC(=O)[C@@H]1Cc2cc(I)c(OCc3cccc(c3)C(F)(F)F)c(I)c2CN1C(=O)c1cccnc1Cl Show InChI InChI=1S/C24H16ClF3I2N2O4/c25-21-15(5-2-6-31-21)22(33)32-10-16-13(9-18(32)23(34)35)8-17(29)20(19(16)30)36-11-12-3-1-4-14(7-12)24(26,27)28/h1-8,18H,9-11H2,(H,34,35)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn Company Curated by ChEMBL					Assay Description Compound was measured for its inhibitory activity against Cell division cycle 25B				Bioorg Med Chem Lett 10: 649-52 (2000) BindingDB Entry DOI: 10.7270/Q2KS6QRN
					More data for this Ligand-Target Pair