BDBM50087227 (S)-6,8-Diiodo-7-(4-trifluoromethyl-benzyloxy)-2-[(E)-3-(2-trifluoromethyl-phenyl)-acryloyl]-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid::CHEMBL158436

SMILES: OC(=O)[C@@H]1Cc2cc(I)c(OCc3ccc(cc3)C(F)(F)F)c(I)c2CN1C(=O)\C=C\c1ccccc1C(F)(F)F

InChI Key: InChIKey=TZBLCBAJUNYMKJ-FNNXTJRKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50087227 ((S)-6,8-Diiodo-7-(4-trifluoromethyl-benzyloxy)-2-[...) Show SMILES OC(=O)[C@@H]1Cc2cc(I)c(OCc3ccc(cc3)C(F)(F)F)c(I)c2CN1C(=O)\C=C\c1ccccc1C(F)(F)F Show InChI InChI=1S/C28H19F6I2NO4/c29-27(30,31)18-8-5-15(6-9-18)14-41-25-21(35)11-17-12-22(26(39)40)37(13-19(17)24(25)36)23(38)10-7-16-3-1-2-4-20(16)28(32,33)34/h1-11,22H,12-14H2,(H,39,40)/b10-7+/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn Company Curated by ChEMBL					Assay Description Compound was measured for its inhibitory activity against Cell division cycle 25B				Bioorg Med Chem Lett 10: 649-52 (2000) BindingDB Entry DOI: 10.7270/Q2KS6QRN
					More data for this Ligand-Target Pair