BDBM50087435 (E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carboxylic acid::8-Hydroxy-2-[2-(4-hydroxy-phenyl)-vinyl]-quinoline-7-carboxylic acid::8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carboxylic acid::CHEMBL418613

SMILES: OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O

InChI Key: InChIKey=DXDQPFWGDWVGIG-LZCJLJQNSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50087435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in 3'-end- processing				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris-Sud Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Integrase in strand transfer(integration)				J Med Chem 43: 1533-40 (2000) BindingDB Entry DOI: 10.7270/Q2JS9PNQ
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jadavpur University Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase 3' processing activity				Eur J Med Chem 43: 81-92 (2008) Article DOI: 10.1016/j.ejmech.2007.02.021 BindingDB Entry DOI: 10.7270/Q24170XZ
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Compound was tested in vitro to inhibit human immuno virus-1 (HIV-1) using enzymatic disintegration assay.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Gag-Pol polyprotein (Rous sarcoma virus (strain Prague C) (RSV-PrC))	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 8532 Curated by ChEMBL					Assay Description Inhibition of rous sarcoma virus (RSV) Integrase.				J Med Chem 43: 1949-57 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2RB759N
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50087435 ((E)-8-hydroxy-2-(4-hydroxystyryl)quinoline-7-carbo...) Show SMILES OC(=O)c1ccc2ccc(\C=C\c3ccc(O)cc3)nc2c1O Show InChI InChI=1S/C18H13NO4/c20-14-8-2-11(3-9-14)1-6-13-7-4-12-5-10-15(18(22)23)17(21)16(12)19-13/h1-10,20-21H,(H,22,23)/b6-1+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris Sud Curated by ChEMBL					Assay Description Inhibition of PIM1				Bioorg Med Chem Lett 20: 2801-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.061 BindingDB Entry DOI: 10.7270/Q2125STS
					More data for this Ligand-Target Pair