BDBM50087513 (R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,2-diol::2-fluoronorepinehprine::CHEMBL40317
SMILES: NC[C@H](O)c1cc(O)c(O)cc1F
InChI Key: InChIKey=SBUQBFTXTZSRMH-QMMMGPOBSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Beta-2 adrenergic receptor (Homo sapiens (Human)) | BDBM50087513 ((R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from human adrenergic beta2 receptor expressed in CHO cell membrane | Bioorg Med Chem 17: 7987-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.015 BindingDB Entry DOI: 10.7270/Q2K35TQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50087513 ((R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding of [3H]-dihydroalprenolol to beta-1 adrenergic receptor of rat cerebral cortical membranes | J Med Chem 43: 1611-9 (2000) BindingDB Entry DOI: 10.7270/Q25M64ZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-2 adrenergic receptor (Canis familiaris) | BDBM50087513 ((R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding of [3H]-dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes | J Med Chem 43: 1611-9 (2000) BindingDB Entry DOI: 10.7270/Q25M64ZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic alpha1B (Homo sapiens (Human)) | BDBM50087513 ((R)4-(2-Amino-1-hydroxy-ethyl)-5-fluoro-benzene-1,...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]prazosin from human adrenergic Alpha-1B receptor expressed in CHO cell membrane | Bioorg Med Chem 17: 7987-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.015 BindingDB Entry DOI: 10.7270/Q2K35TQ5 | |||||||||||
More data for this Ligand-Target Pair |