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BDBM50087668 10-[2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-benzoyl]-10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepine-3-carboxylic acid::CHEMBL350408

SMILES: Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3ccc(C(O)=O)n3Cc3ccccc23)c(Cl)c1

InChI Key: InChIKey=RLNGMJLEEPCPAQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087668   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vasopressin V2 receptor


(Homo sapiens (Human))		BDBM50087668
PNG
(10-[2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-be...)
Show SMILES Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3ccc(C(O)=O)n3Cc3ccccc23)c(Cl)c1
Show InChI InChI=1S/C28H21ClFN3O4/c1-16-6-7-18(30)12-22(16)26(34)31-19-8-10-21(23(29)13-19)27(35)33-15-20-9-11-25(28(36)37)32(20)14-17-4-2-3-5-24(17)33/h2-13H,14-15H2,1H3,(H,31,34)(H,36,37)
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n/an/a 14n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes

Bioorg Med Chem Lett 10: 783-6 (2000)


BindingDB Entry DOI: 10.7270/Q24M93RK
More data for this
Ligand-Target Pair